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Studies on polynucleotide biosynthesis.

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  • The basic investigations which led to the discovery of the nucleic acids were made by Friedrich Miescher (1), who as a student of Hoppe-Seyler in 1868, became interested in the problem of isolating nuclear components. He was able to prepare nuclei from pus cells obtained from discarded surgical bandages. From this nuclear material he was able to prepare an unusual phosphorous containing compound which he named "nuclein". At that time, the only known natural source of organic phosphorous was lecithin, and so this discovery alone was sufficient to attract attention to the compound.
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  • 2025-03-20
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  • McGill University
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